The commencement of the round of 64 in the 2026 NCAA Division I Men’s Basketball Tournament, colloquially known as March Madness, is scheduled for Thursday, featuring a total of 16 matchups that will unfold throughout the day. Among the contenders, the premier seeds from Duke and Michigan will be prominently engaged in their initial clashes.

Duke and Michigan embark on their March Madness campaigns

Opening the competitive proceedings in the East region, the Duke Blue Devils initiate their quest to secure a sixth national championship. Their first opponent in this endeavor will be the Siena Saints, with the game set to take place at the Capital One Arena in Washington, D.C.

Simultaneously, in the Midwest region, the Michigan Wolverines will commence their pursuit of March Madness triumph, facing off against the Howard Bison. This marks a significant moment for Michigan, as it comes 37 years after their only national title was claimed.